Papain is a mixture of proteolytic enzymes derived from the juice of the unripe fruit of the tropical plant Caroica papaya, commonly known as papaya. Papain is a protein-cleaving enzyme derived from papaya and a few other plants. These enzymes are complex molecules produced in living organisms to catalyze (speed up) chemical reactions within the cell. A number of digestive enzyme supplements are available. The simple ones are extracted from tropical fruits: bromelain from pineapple and papain from papayas. Papain has a mild, soothing effect on the stomach and aids in protein digestion. Papain is used as a digestive aid and has putative anti-inflammatory activity.